E-ISSN: 1307-394X
Assessment of Serum Interleukin-4 and Immunoglobin E Levels in Pityriasis Alba Patients
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Research
VOLUME: 7 ISSUE: 2
P: 0-0
June 2013

Assessment of Serum Interleukin-4 and Immunoglobin E Levels in Pityriasis Alba Patients

J Turk Acad Dermatol 2013;7(2):0-0
DOI: 10.6003/jtad.1372a1
Tahreer A. A. Al-mesari 1
Amal H. A. Gomaa 1
Alaael-din S. Abd-el-hamid 2
Ghada F. A. Mohammed 1
Moustafa M. K. Eyada 1
1. Department of Dermatology and Venereology,
2. Department of Clinical Pathology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
No information available.
No information available
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ABSTRACT

Background:

Role of IL-4 and Ig-E in aetiopathogenesis of pityriasis alba (PA) is questionable.

Aim:

To assess the serum IL-4 and Ig-E levels in pityriasis alba patients.

Patients & Methods:

Thirty patients with pityriasis alba (group I) (n=30) and thirty volunteers (group II) completed the study (n=30). IL-4 and Ig-E were measured in patients’ sera with enzyme linked immune sorbent assay (ELISA).

Results:

There was statistically significant correlation between IL-4 and PA which points to the role of Th2 and IL-4 in pathogenesis of PA. There was no statistically significance between Ig-E and either PA or IL-4 level.

Conclusion:

Imbalance of IL-4 level may play a critical role in pathogenesis of PA. Changed balance of IL-4 level may be related to the genetic background of patients, and adds more evidence to the association of PA and atopic dermatitis.