ABSTRACT

Observation:

We report the case of a 22-year-old male with a diagnosis of Crohn’s disease who developped palmoplantar pustular psoriasis under 15th month of infliximab treatment. While antitumour necrosis factor (anti-TNF)-alpha therapy is an effective treatment option for psoriasis, there are reports of occurrence or aggravation of psoratic eruptions with these agents. De novo skin lesions in our patient without a personal or family history of psoriasis was diagnosed as paradoxical palmoplantar pustular psoriasis.