ABSTRACT

Lichen sclerosus is a chronic inflammatory disease with a predisposition of the anogenital region. Topical corticosteroid is effective; however, a continuous treatment is often required. After its stoppage the recurrence is often and the side effects of repeated local application of potent glucocorticosteroids may be seen that is why an equally-effective, safer therapeutic options are needed, especially in the treatment of children.

Here, we report a case of vulvar lichen sclerosus in a 6-year-old girl refracted to topical steroid. After 12 weeks of treatment with 0.03% tacrolimus ointment once daily, the lesions get resolved without any side-effects. This is our first case of topical tacrolimus treatment showing a dramatic effect in the treatment of childhood vulvar lichen sclerosus.