ABSTRACT

Background:

Hidradenitis suppurativa (HS), known as acne inversa, is a relapsing and chronic inflammatory skin disease affecting the skin folds. Scarring and infection are the most common complications that also cause a significant morbidity and impair the quality of life of these patients. Local complications of the disease include the development of strictures in the local scars, anus, urethra or rectum, which may result in limitation of movement; genital edema that may cause functional impairment. All wounds that can not complete the natural healing process have potential for developing dysplastic changes. There is also a risk of developing squamous cell carcinoma in HS patients with refractory disease with prolonged courses. Treatment depends on the stage, frequency of exacerbation and the goal of the patient. Tobacco cessation, weight reduction, control of cardiovascular risk factors, avoidance of the use of irritants in affected areas, hair removal using lasers are elementary precautions which can be taken. Unfortunately, HS one single treatment modality that has sufficient efficacy or treatment modality. Today, systemic agents including oral antibiotics, retinoids, androgens and biological agent, surgical procedures and lasers are used in the management of HS. In this review, clinical findings along with accompanying diseases and treatments are discussed, in the light of the current literature