Observation:
Interferon-alpha (INF) or peginterferon alpha (PEG IFN) and ribavirin combination therapy in chronic hepatitis C virus (HCV) infection is recognized as an effective treatment method. Skin related side effects have rarely been reported during chronic HCV infection treatments and they usually are lesions seen in the local injection sites. We present a case with HCV infection that occurred in the sun-exposed areas and axillar area by secondary pigmentation during PEG-INF-2a plus and ribavirin combination therapy.
Keywords: HCV infection, hyperpigmentation, peginterferonalpha-2a