Case Report

From Multiple Dermatofibroma to Spindle Cell Sarcoma Different Types of Fibrohistiocytic Tumors in Same Patient


  • Tuğba Kevser Uzunçakmak
  • Ayşe Serap Karadağ
  • Bengü Nisa Akay
  • Ayşe Bahar Ceyran
  • Necmettin Akdeniz

J Turk Acad Dermatol 2019;13(4):0-0


Dermatofibroma is a benign fibrohistiocytic tumour of skin which is also known as benign fibrous histiocytoma. It is usually seen in adults in lower extremities and as a solitary, pink to brownish papulonodular lesion that may vary in number and size. Multiple dermatofibromas are rarely seen and have been reported as congenital clustered dermatofibromas or acquired associated with autoimmune diseases, immunsuppression and different malignancies in the literature


A 49 year-old male patient with multiple reddish to brown, rigorous lesions on his back and hips with a history of two years. He had three surgeries for soft tissue tumours on his left leg and left lung two years ago which were consistent with low grade fibromyxoid sarcoma and solitary fibrous tumour/ hemagiopericytoma histologically. Dermatoscopic examination of papulonodular lesions were consistent with dermatofibroma. In regard to his past medical history, punch biopsies were performed to both lesions. Histopathological examinations of the lesions were both consistent with dermatofibroma. Multiple dermatofibroma and sarcoma association has not been reported in the literature before. We also present this case because of rare occurence of multiple benign and malignant fibrohistiocytics tumours concominantly.

Keywords: Benign Fibrous Histocytoma, Dermatofibroma, low Grade Fibromyxoid Sarcoma, Solitary Fibrous Tumour