Case Report

A Case of Generalized Flegel Disease Successful Treatment with Acitretin


  • Ayşe Serap Karadağ
  • Mukaddes Kavala
  • Ebru Zemheri
  • Şeyma Özkanlı
  • Berkant Oman
  • Zafer Türkoğlu
  • İlkin Zindancı

J Turk Acad Dermatol 2014;8(4):0-0


Hyperkeratosis lenticularis perstans (HLP) known as Flegel's disease is a rare keratinization disorder characterized by asymptomatic, small, reddish-brown keratotic papules with horny scales. In unusual variant, the trunk involvement has been reported as well. Here we report 80-year old woman presenting with generalized hyperkeratotic horny papules on her body. The clinical and histopathological findings were consistent with HLP. We report a case presenting with widespread Flegel’s disease who responded to acitretin treatment.

Keywords: Acitretin, Flegel disease, keratinization disorder