Observation:
Lichen planus is a T-cell mediated chronic mucocutaneous disorder of unknown etiology. Occasionally, genital area involvement may be the sole manifestation of the disease. First-line treatment is topical corticosteroids, but some cases may not respond to these agents. A 50-year-old male patient presenting with gray-white reticular lesions on the penis was given a clinical diagnosis of lichen planus and the patient showed clearance of the lesions at the end of treatment with pimecrolimus %1 cream. Topical pimecrolimus may be a useful second-line therapeutic option for genital lichen planus unresponsive to topical corticosteroids and it may induce sustained remissions.
Keywords: Penile lichen planus, topical calcineurin inhibitors, topical pimecrolimus